binding
The definitions used in this glossary of terminology either have been provided by the authors of the articles, or have been extracted wholly or in part, or paraphrased from the following sources: The American Medical Association Encyclopedia of Medicine, Charles B. Clayman, MD, Medical Editor, Random House, New York, 1989; Biotechnology from A to Z, 2d Edition, William Bains, Oxford University Press, New York, New York, 2002; A Dictionary of Genetics, 6th Edition, Robert C. King and William D. Stansfield, Oxford University Press, New York, New York, 2002; Dorland's Illustrated Medical Dictionary, 29th and 30th Editions, W. B. Saunders Company, Philadelphia, 2000, 2003; Genes VII, Benjamin Lewin, Oxford University Press, New York, New York, 2000; The Gale Encyclopedia of Genetic Disorders, Volumes I and II, Stacey L. Blachford, Ed., Thomson Learning, New York, New York, 2002; The Merriam-Webster Dictionary, Merriam-Webster, Inc., Springfield, Massachusetts, 1997; Molecular Biology of the Cell, 3rd Edition, Bruce Alberts, et al., Garland Publishing, 1994; The Random House Dictionary of the English Language, Unabridged Edition, 1966; Webster's Ninth New Collegiate Dictionary, 1991.
DEFINITION:
- binding
Used in 51 Article abstracts
Used in 51 Article abstracts
- 125I-d(CH2)5[Tyr(Me)2, Tyr(NH2)9]AVP: Iodination and Binding Characteristics of a Vasopressin Receptor Ligand
- A Dileucine Sequence and an Upstream Glutamate Residue in the Intracellular Carboxyl Terminus of the Vasopressin V2 Receptor are Essential for Cell Surface Transport in COS.M6 Cells
- A Low Affinity Vasopressin V2-Receptor in Inherited Nephrogenic Diabetes Insipidus
- A Specific Antibody to Vasopressin in a Man with Concomitant Resistance to Treatment with Pitressin
- Agonist and Antagonist-Dependent Internalization of the Human Vasopressin V2 Receptor
- Annexin A4 Reduces Water and Proton Permeability of Model Membranes but Does Not Alter Aquaporin 2-mediated Water Transport in Isolated Endosomes
- Atrial Natriuretic Factor Inhibits Vasopressin-Stimulated Osmotic Water Permeability in Rat Inner Medullary Collecting Duct
- Binding-, Intracellular Transport-, and Biosynthesis-Defective Mutants of Vasopressin Type 2 Receptor in Patients with X-Linked Nephrogenic Diabetes Insipidus
- Calcineurin-NFATc Signaling Pathway Regulates AQP2 Expression in Response to Calcium Signals and Osmotic Stress
- Chlorpropamide Upregulates Antidiuretic Hormone Receptors and Unmasks Constitutive Receptor Signaling
- Cloned Human Aquaporin-1 is a Cyclic GMP-gated Ion Channel
- Constitutive Arrestin-Mediated Desensitization of a Human Vasopressin Receptor Mutant Associated with Nephrogenic Diabetes Insipidus
- Derivatives of Somatic Cell Hybrids Which Carry the Human Gene Locus for Nephrogenic Diabetes Insipidus (NDI) Express Functional Vasopressin Renal V2-type Receptors
- Downregulation of Aquaporin-2 and -3 in Aging Kidney is Independent of V2 Vasopressin Receptor
- Endocytosis in Renal Proximal Tubules. Experimental Electron Microscopical Studies of Protein Absorption and Membrane Traffic in Isolated, In Vitro Perfused Proximal Tubules
- Evidence for Intact V1-vasopressin Receptors in Congenital Nephrogenic Diabetes Insipidus
- Expression Studies of Two Vasopressin V2 Receptor Gene Mutations, R202C and 804insG, in Nephrogenic Diabetes Insipidus
- First Intracellular Loop of the Human Cholecystokinin-A Receptor is Essential for Cyclic AMP Signaling in Transfected HEK-293 Cells
- Folding and Cell Surface Expression of the Vasopressin V2 Receptor: Requirement of the Intracellular C-terminus
- Functional Characterization of Five V2 Vasopressin Receptor Gene Mutations
- G-Protein-Coupled Receptors: Molecular Mechanisms Involved in Receptor Activation and Selectivity of G-Protein Recognition
- Hereditary Vasopressin Resistance in Man and Mouse
- Human Platelet Fraction Arginine-Vasopressin. Potential Physiological Role
- Identification of Agonist Binding Sites of Vasopressin and Oxytocin Receptors
- Identification of a Multiprotein "Motor" Complex Binding to Water Channel Aquaporin-2
- In Vitro Micro-Autoradiography of Atrial Natriuretic Peptide in Biopsy Specimens from Patients with Renal Diseases
- Maturation of Receptor Proteins in Eukaryotic Expression Systems
- Mechanisms and Regulation of Water Permeability in Renal Epithelia
- Molecular Mechanisms and Drug Development in Aquaporin Water Channel Diseases: Molecular Mechanism of Water Channel Aquaporin-2 Trafficking
- Molecular Pathogenesis of Nephrogenic Diabetes Insipidus
- Nephrogenic Diabetes Insipidus: Functional Analysis of New AVPR2 Mutations Identified in Italian Families
- Novel Down-Regulatory Mechanism of the Surface Expression of Vasopressin V2 Receptor by an Alternative Splice Receptor Variant
- Pharmacochaperones Post-Translationally Enhance Cell Surface Expression by Increasing Conformational Stability of Wild-Type and Mutant Vasopressin V2 Receptors
- Pharmacological Chaperones Rescue Cell-Surface Expression and Function of Misfolded V2 Vasopressin Receptor Mutants
- Pharmacological Chaperones in Nephrogenic Diabetes Insipidus: Possibilities for Clinical Application
- Platelet Vasopressin Receptors in Patients With Congenital Nephrogenic Diabetes Insipidus
- Properties of the Human Arginine Vasopressin V2 Receptor after Site-Directed Mutagenesis of its Putative Palmitoylation Site
- Regional Time-Dependent Changes in Vasopressin V2 Receptor Expression in the Rat Kidney During Water Restriction
- Regulation of Collecting Duct Water Permeability Independent of cAMP-Mediated AVP Response
- Requirement of Human Renal Water Channel Aquaporin-2 for Vasopressin-Dependent Concentration of Urine
- Routing of the aquaporin-2 water channel in health and disease.
- The 17 kDa Band Identified by Multiple Anti-Aquaporin 2 Antisera in Rat Kidney Medulla is a Histone
- The Effect of Eight V2 Vasopressin Receptor Mutations on Stimulation of Adenylyl Cyclase and Binding to Vasopressin
- The Property of a Novel V2 Receptor Mutant in a Patient with Nephrogenic Diabetes Insipidus
- Two Vasopressin Type 2 Receptor Gene Mutations R143P and Delta V278 in Patients with Nephrogenic Diabetes Insipidus Impair Ligand Binding of the Receptor
- V2 Vasopressin Receptor Dysfunction in Nephrogenic Diabetes Insipidus Caused By Different Molecular Mechanisms
- Variant Amino Acids in the Extracellular Loops of Murine and Human Vasopressin V2 Receptors Account for Differences in Cell Surface Expression and Ligand Affinity
- Vasopressin Receptor Mutations and Nephrogenic Diabetes Insipidus
- Vasopressin Type-2 Receptor and Aquaporin-2 Water Channel Mutants in Nephrogenic Diabetes Insipidus
- Vasopressin V2 Receptor Mutants that Cause X-linked Nephrogenic Diabetes Insipidus: Analysis of Expression, Processing, and Function
- Water Channel Aquaporin-2 Directly Binds to Actin
Used in 8 Article bodies
Used in 8 Article bodies
- A Novel Polymorphism in the Coding Region of the Vasopressin Type 2 Receptor Gene
- Analysis of Vasopressin Receptor Type II (V2R) Gene in Three Japanese Pedigrees with Congenital Nephrogenic Diabetes Insipidus: Identification of a Family with Complete Deletion of the V2R Gene
- Hereditary Vasopressin Resistance in Man and Mouse
- Importance of the Mercury-Sensitive Cysteine on Function and Routing of AQP1 and AQP2 in Oocytes
- Inborn Errors of Signal Transduction: Mutations in G Proteins and G Protein-coupled Receptors as a Cause of Disease
- Molecular Analysis of X-Linked Nephrogenic Diabetes Insipidus
- Nephrogenic Diabetes Insipidus
- Role of Aquaporin-2 Water Channels in Urinary Concentration and Dilution Defects
Used in 82 Article translations
Used in 82 Article translations
- A Fully Active Nonglycosylated V2 Vasopressin Receptor
- A Low-Affinity Vasopressin V2-Receptor Gene in a Kindred with X-Linked Nephrogenic Diabetes Insipidus
- A Role for K268 in V2R Folding
- An Extracellular Congenital Nephrogenic Diabetes Insipidus Mutation of the Vasopressin Receptor Reduces Cell Surface Expression, Affinity for Ligand, and Coupling to the Gs/adenylyl Cyclase System
- An X-linked NDI Mutation Reveals a Requirement for Cell Surface V2R Expression
- Angiotensin II AT1 Receptor Blockade Decreases Vasopressin-Induced Water Reabsorption and AQP2 Levels in NaCl-Restricted Rats
- Bilateral Ureteral Obstruction Downregulates Expression of Vasopressin-Sensitive AQP-2 Water Channel in Rat Kidney
- Binding-, Intracellular Transport-, and Biosynthesis-Defective Mutants of Vasopressin Type 2 Receptor in Patients with X-Linked Nephrogenic Diabetes Insipidus
- Characterization of Vasopressin V2 Receptor Mutants in Nephrogenic Diabetes Insipidus in a Polarized Cell Model
- Comparative Mapping on the Mouse and Human X Chromosomes of a Human cDNA Clone Encoding the Vasopressin Renal-Type Receptor (AVP2R)
- Congenital Nephrogenic Diabetes Insipidus
- Congestive Heart Failure in Rats is Associated with Increased Expression and Targeting of Aquaporin-2 Water Channel in Collecting Duct
- Cross Talk Between Stimulatory and Inhibitory Guanosine 5'-Triphosphate Binding Proteins: Role in Activation and Desensitization of the Adenylate Cyclase Response to Vasopressin
- Defects of G Protein-Coupled Signal Transduction in Human Disease
- Dehydration Reverses Vasopressin Antagonist-Induced Diuresis and Aquaporin-2 Downregulation in Rats
- Derivatives of Somatic Cell Hybrids Which Carry the Human Gene Locus for Nephrogenic Diabetes Insipidus (NDI) Express Functional Vasopressin Renal V2-type Receptors
- Desensitization of the Human V2 Vasopressin Receptor. Homologous Effects in the Absence of Heterologous Desensitization
- Differential Diagnosis and Pathophysiology of Diabetes Insipidus
- Downregulation of Aquaporin-2 Parallels Changes in Renal Water Excretion in Unilateral Ureteral Obstruction
- Dual Actions of Vasopressin and Oxytocin in Regulation of Water Permeability in Terminal Collecting Duct
- Effect of DDAVP on Nocturnal Enuresis in a Patient with Nephrogenic Diabetes Insipidus
- Effects of Arginine Vasopressin and 1-Desamino-8-D Arginine Vasopressin on Forearm Vasculature of Healthy Subjects and Patients with a V2 Receptor Defect
- Epinephrine and dDAVP Administration in Patients with Congenital Nephrogenic Diabetes Insipidus. Evidence for a pre-cyclic AMP V2 Receptor Defective Mechanism
- Evidence for Intact V1-vasopressin Receptors in Congenital Nephrogenic Diabetes Insipidus
- Expression Studies of Two Vasopressin V2 Receptor Gene Mutations, R202C and 804insG, in Nephrogenic Diabetes Insipidus
- Fibrinolytic Responses to 1-desamino-8-D-arginine-vasopressin in Patients with Congenital Nephrogenic Diabetes Insipidus
- Folding and Cell Surface Expression of the Vasopressin V2 Receptor: Requirement of the Intracellular C-terminus
- Functional Characterization of Five V2 Vasopressin Receptor Gene Mutations
- Functional Rescue of Mutant V2 Vasopressin Receptors Causing Nephrogenic Diabetes Insipidus by a Co-Expressed Receptor Polypeptide
- Functional Rescue of Vasopressin V2 Receptor Mutants in MDCK Cells by Pharmacochaperones: Relevance to Therapy of Nephrogenic Diabetes Insipidus
- Functional Rescue of the Constitutively Internalized V2 Vasopressin Receptor Mutant R137H by the Pharmacological Chaperone Action of SR49059
- Functional Role of the NPxxY Motif in Internalization of the Type 2 Vasopressin Receptor in LLC-PK1 Cells
- G-Protein-Coupled Receptors: Molecular Mechanisms Involved in Receptor Activation and Selectivity of G-Protein Recognition
- Heat Shock Protein 70 Interacts with Aquaporin-2 (AQP2) and Regulates Its Trafficking
- Heterogeneous AVPR2 Gene Mutations in Congenital Nephrogenic Diabetes Insipidus
- Hyponatremia and Hypernatremia
- Identification and Characterization of Aquaporin-2 Water Channel Mutations Causing Nephrogenic Diabetes Insipidus with Partial Vasopressin Response
- Identification of a Multiprotein "Motor" Complex Binding to Water Channel Aquaporin-2
- In Vitro Micro-Autoradiography of Atrial Natriuretic Peptide in Biopsy Specimens from Patients with Renal Diseases
- Inborn Errors of Signal Transduction: Mutations in G Proteins and G Protein-coupled Receptors as a Cause of Disease
- Increased Renal Responsiveness to Vasopressin and Enhanced V2 Receptor Signaling in RGS2-/- Mice
- Inhibition of Endocytosis Causes Phosphorylation (S256)-Independent Plasma Membrane Accumulation of AQP-2
- Membrane Targeting and Determination of Transmembrane Topology of the Human Vasopressin V2 Receptor
- Molecular Cloning of the Receptor for Human Antidiuretic Hormone
- Molecular Mechanisms and Drug Development in Aquaporin Water Channel Diseases: Molecular Mechanism of Water Channel Aquaporin-2 Trafficking
- Molecular and Cellular Biology of Vasopressin and Oxytocin Receptors and Action in the Kidney
- Mutations in the V2 Vasopressin Receptor Gene are Associated with X-linked Nephrogenic Diabetes Insipidus
- Nephrogenic Diabetes Insipidus (Bichet - November 1998)
- Nephrogenic Diabetes Insipidus (Bichet)
- Nephrogenic Diabetes Insipidus Caused By Mutation of Tyr205: A Key Residue of V2 Vasopressin Receptor Function
- Nephrogenic Diabetes Insipidus in Sibling Colts
- Nephrogenic Diabetes Insipidus. A V2 Vasopressin Receptor Unable to Stimulate Adenylyl Cyclase
- Nephrogenic Diabetes Insipidus: Causes Revealed
- Nephrogenic Diabetes Insipidus: Clinical Symptoms, Pathogenesis, Genetics and Treatment
- Nephrogenic Diabetes Insipidus: Identification of the Genetic Defect
- Normal Fibrinolytic Responses to 1-Desamino-8-D-Arginine Vasopressin in Patients with Nephrogenic Diabetes Insipidus Caused by Mutations in the Aquaporin 2 Gene
- Novel Mutations in the V2 Vasopressin Receptor Gene in Two Pedigrees with Congenital Nephrogenic Diabetes Insipidus
- Palmitoylation of the V2 Vasopressin Receptor
- Pathophysiology of Aquaporin-2 in Water Balance Disorders
- Pharmacochaperones Post-Translationally Enhance Cell Surface Expression by Increasing Conformational Stability of Wild-Type and Mutant Vasopressin V2 Receptors
- Pharmacologic Chaperones as a Potential Treatment for X-linked Nephrogenic Diabetes Insipidus
- Pharmacological Chaperones Rescue Cell-Surface Expression and Function of Misfolded V2 Vasopressin Receptor Mutants
- Pharmacological Chaperones in Nephrogenic Diabetes Insipidus: Possibilities for Clinical Application
- Pharmacological Chaperones: Potential Treatment for Conformational Diseases
- Phenotypes Developed in Secretin Receptor-Null Mice Indicated a Role for Secretin in Regulating Renal Water Reabsorption
- Phosphorylation of the V2 Vasopressin Receptor
- Physiology and Pathophysiology of the Aquaporin-2 Water Channel
- Platelet Vasopressin Receptors in Patients With Congenital Nephrogenic Diabetes Insipidus
- Properties of the Human Arginine Vasopressin V2 Receptor after Site-Directed Mutagenesis of its Putative Palmitoylation Site
- Renal Histology in a Patient with Nephrogenic Diabetes Insipidus
- Requirement of Human Renal Water Channel Aquaporin-2 for Vasopressin-Dependent Concentration of Urine
- Rolipram, a Phosphodiesterase Inhibitor, in the Treatment of Two Male Patients with Congenital Nephrogenic Diabetes Insipidus
- Successful Treatment with Hydrochlorothiazide and Amiloride in an Infant with Congenital Nephrogenic Diabetes Insipidus
- The C-Terminal Tail of Aquaporin-2 Determines Apical Trafficking
- The Effect of Eight V2 Vasopressin Receptor Mutations on Stimulation of Adenylyl Cyclase and Binding to Vasopressin
- The Ins and Outs of Aquaporin-2 Trafficking
- Therapeutic Potential of Vasopressin Receptor Antagonists
- Two Novel Mutations in the Vasopressin V2 Receptor Gene in Unrelated Japanese Kindreds with Nephrogenic Diabetes Insipidus
- Two Vasopressin Type 2 Receptor Gene Mutations R143P and Delta V278 in Patients with Nephrogenic Diabetes Insipidus Impair Ligand Binding of the Receptor
- V2 Vasopressin Receptor Dysfunction in Nephrogenic Diabetes Insipidus Caused By Different Molecular Mechanisms
- Vasopressin Type-2 Receptor and Aquaporin-2 Water Channel Mutants in Nephrogenic Diabetes Insipidus
- X-Linked Nephrogenic Diabetes Insipidus Mutations in North America and the Hopewell Hypothesis
Used in 24 Proceeding abstracts
Used in 24 Proceeding abstracts
- Binding properties and cAMP production study of 7 mutant V2 receptors related to cNDI
- Characterization of mutant vasopressin V2 receptors with a misfolded AVP binding site
- Clinical Data and Cell Biological Aspects of Mutations in Nephrogenic Diabetes Insipidus
- Comparative analysis of human and murine vasopressin V2 receptor genes and their encoded proteins reveal striking differences in their genomic structure and functional properties
- Differences between ER-retained vasopressin V2 receptor mutants in antagonist-mediated restoration of cell surface expression
- Effects of Carbenoxolone on Sodium Transporter and Aquaporin-2 Abundance in Kidney
- G15 reveals coupling of the V2 receptor to PLC that is refractory to receptor desensitization
- Impaired routing of AQP2 to late endosomes/lysosomes following heterotetramerization with AQP2-E258K is likely to explain dominant nephrogenic diabetes insipidus
- Long-term regulation of aquaporin-2: a possible therapeutic approach to NDI?
- Mutations of the vasopressin V2 receptor gene in X-linked Nephrogenic Diabetes Insipidus: functional analysis of receptor mutants and identification of new mutations in Italian families.
- Naturally occurring and in vitro mutations defining the role of the NPXXY motif in the vasopressin V2 receptor
- Nephrogenic Diabetes Insipidus Mutation Database
- Osmolality and solute composition regulate aquaporin-2 expression in primary cultured renal principal cells
- Pharmacological chaperones functionally rescue misfolded mutant V2 vasopressin receptors that cause nephrogenic diabetes insipidus
- Production and purification of Aquaporin-2 and Vasopressin 2 Receptor: towards elucidation of the structure
- Progress in the function and structure of aquaporin-1 and aquaporin-2
- Role of phosphorylation in the trafficking and shuttling of the Aquaporin-2 water channel
- Routing and function of mutant AQP2 water channels in nephrogenic diabetes insipidus
- The novel Aquaporin-2 maturing protein 1 interacts with AQP2, inhibits its forskolin-induced translocation to the apical membrane, and reduces its expression
- V2 Vasopressin Receptors in NDI: Where did they go?
- V2 vasopressin receptor dysfunction in patients with nephrogenic diabetes insipidus is caused by different molecular mechanisms
- V2 vasopressin receptor mutants responsible for nephrogenic diabetes insipidus associate with the molecular chaperones calnexin and Hsp70
- V2 vasopressin receptor-arrestin interactions
- cDNA Array Analysis Identifies Vasopressin Regulation of 11 bHSD-2 in Rat Renal Collecting Duct
Used in 16 Proceeding translations
Used in 16 Proceeding translations
- Rescue of the Cell Surface Expression of Vasopressin V2 Receptor Mutants in Nephrogenic Diabetes Insipidus
- Binding properties and cAMP production study of 7 mutant V2 receptors related to cNDI
- Characterization of mutant vasopressin V2 receptors with a misfolded AVP binding site
- Clinical Data and Cell Biological Aspects of Mutations in Nephrogenic Diabetes Insipidus
- Comparative analysis of human and murine vasopressin V2 receptor genes and their encoded proteins reveal striking differences in their genomic structure and functional properties
- Consequences of tetramerization and expression levels of Aquaporin-2 in phenotype-genotype correlation studies in autosomal NDI
- G15 reveals coupling of the V2 receptor to PLC that is refractory to receptor desensitization
- Identification of proteins involved in the vasopressin-induced shuttle of aquaporin-2
- Long-term regulation of aquaporin-2: a possible therapeutic approach to NDI?
- Molecular mechanisms underlying dominant Nephrogenic Diabetes Insipidus caused by mutations in the AQP2 gene
- Mono-ubiquitination and missorting to lysosomes of the Aquaporin-2 water channel mutant AQP2-E258K explains dominant Nephrogenic Diabetes Insipidus
- Progress in the function and structure of aquaporin-1 and aquaporin-2
- Regulation and distribution of phosphorylated aquaporin-2 (AQP2) in rat kidney collecting duct principal cells
- Regulation of Aquaporin-2 trafficking by Vasopressin in Renal Collecting Duct: Roles of Ryanodine-Sensitive Ca2+ Stores and Calmodulin
- Routing and function of mutant AQP2 water channels in nephrogenic diabetes insipidus
- The novel Aquaporin-2 maturing protein 1 interacts with AQP2, inhibits its forskolin-induced translocation to the apical membrane, and reduces its expression
Used in 39 Term definitions
Used in 39 Term definitions
- CTL
- ELISA
- Fc
- NDI Abstract of Article: 538
- albumin
- aminoglycoside
- aminoglycosides
- antagonist
- antagonists
- antagonize
- antigen-antibody reaction
- banding
- blank
- bound
- carrier
- conjugated
- cytochrome c oxidase
- cytotoxic T lymphocytes
- gate
- gene repression
- immunoassay
- immunoglobulins
- ligand
- ligands
- mutant receptors
- neurophysins
- nitric oxide
- null
- opsonin
- orbital fascia
- protein kinase C
- receptor
- recognition
- steroid hormones
- tethering
- transporter
- transporters
- valence
- variable region



